Cargando…

Excess Soluble CD40L Contributes to Blood Brain Barrier Permeability In Vivo: Implications for HIV-Associated Neurocognitive Disorders

Despite the use of anti-retroviral therapies, a majority of HIV-infected individuals still develop HIV-Associated Neurocognitive Disorders (HAND), indicating that host inflammatory mediators, in addition to viral proteins, may be contributing to these disorders. Consistently, we have previously show...

Descripción completa

Detalles Bibliográficos
Autores principales:	Davidson, Donna C., Hirschman, Michael P., Sun, Anita, Singh, Meera V., Kasischke, Karl, Maggirwar, Sanjay B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520914/ https://www.ncbi.nlm.nih.gov/pubmed/23251626 http://dx.doi.org/10.1371/journal.pone.0051793

Ejemplares similares

Targeting platelet-derived soluble CD40 ligand: a new treatment strategy for HIV-associated neuroinflammation?
por: Davidson, Donna C, et al.
Publicado: (2013)

Valproic Acid Inhibits the Release of Soluble CD40L Induced by Non-Nucleoside Reverse Transcriptase Inhibitors in Human Immunodeficiency Virus Infected Individuals
por: Davidson, Donna C., et al.
Publicado: (2013)

Soluble CD40 ligand directly alters glomerular permeability and may act as a circulating permeability factor in FSGS
por: Doublier, Sophie, et al.
Publicado: (2017)

The role of soluble CD40L in immunosuppression
por: Schlom, Jeffrey, et al.
Publicado: (2013)

Levels of human platelet-derived soluble CD40 ligand depend on haplotypes of CD40LG-CD40-ITGA2
por: Aloui, Chaker, et al.
Publicado: (2016)

Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice
por: Singh, Vir B., et al.
Publicado: (2016)

Lactate Fuels the Neonatal Brain
por: Kasischke, Karl
Publicado: (2011)

The Contribution of CD40/CD40L Axis in Inflammatory Bowel Disease: An Update
por: Senhaji, Nezha, et al.
Publicado: (2015)

Solubility and Permeability Enhancement of Oleanolic Acid by Solid Dispersion in Poloxamers and γ-CD
por: De Stefani, Chiara, et al.
Publicado: (2022)

Association of soluble CD40 levels with ‐1 C > T CD40 polymorphism and chronic kidney disease in systemic lupus erythematosus
por: Tapia‐Llanos, Raziel, et al.
Publicado: (2019)

Soluble CD40 ligand is not solely related to the presence and severity of sepsis
por: Chew, Michelle S, et al.
Publicado: (2011)

Childhood trauma and genetic variation in the DAT 40-bp VNTR contribute to HIV-associated neurocognitive disorders
por: Roomaney, Aqeedah Abbas, et al.
Publicado: (2021)

Soluble CD40 Ligand in Aspirin-Treated Patients Undergoing Cardiac Catheterization
por: Gremmel, Thomas, et al.
Publicado: (2015)

Soluble CD40 Ligand Levels in Children with Newly Diagnosed Graves’ Disease
por: Metwalley, Kotb Abbass, et al.
Publicado: (2020)

The Proinflammatory Soluble CD40 Ligand Is Associated with the Systemic Extent of Stable Atherosclerosis
por: Pereira-da-Silva, Tiago, et al.
Publicado: (2021)

Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation
Publicado: (1993)

Analysis of Genetic Variation in CD40 and CD40L: Relationship with mRNA Relative Expression and Soluble Proteins in Acute Coronary Syndrome
por: Martínez-Fernández, D. E., et al.
Publicado: (2019)

SuperGAG biopolymers for treatment of excessive bladder permeability
por: Towner, Rheal A., et al.
Publicado: (2021)

Modeling HIV-1 Induced Neuroinflammation in Mice: Role of Platelets in Mediating Blood-Brain Barrier Dysfunction
por: Jones, Letitia D., et al.
Publicado: (2016)

Contribution of Elevated Glucose and Oxidized LDL to Macrophage Inflammation: A Role for PRAS40/Akt-Dependent Shedding of Soluble CD14
por: Sanjurjo, Lucía, et al.
Publicado: (2023)

Holey barrier: claudins and the regulation of brain endothelial permeability
por: Matter, Karl, et al.
Publicado: (2003)

CD40 expression in the hippocampus and its role in blood-brain barrier permeability, neutrophil infiltration and oxidative stress: implication for brain damage associated with sepsis in rats
por: Michels, Monique, et al.
Publicado: (2013)

Blood–spinal cord barrier pericyte reductions contribute to increased capillary permeability
por: Winkler, Ethan A, et al.
Publicado: (2012)

Soluble CD4 effectively prevents excessive TLR activation of resident macrophages in the onset of sepsis
por: Zhang, Sheng-yuan, et al.
Publicado: (2023)

Soluble CD40 Ligand Levels in Otherwise Healthy Subjects With Impaired Fasting Glucose
por: Tasci, Ilker, et al.
Publicado: (2006)

Soluble CD40 ligand, a mediator of sepsis or of transfusion-related adverse effects?
por: Tuinman, Pieter R, et al.
Publicado: (2011)

Soluble CD40 ligand and prolactin levels in migraine patients during interictal period
por: Guldiken, Sibel, et al.
Publicado: (2011)

Serum soluble CD40 is associated with liver injury in patients with chronic hepatitis B
por: SHEN, HONG-HUI, et al.
Publicado: (2015)

LPS stimulation of purified human platelets is partly dependent on plasma soluble CD14 to secrete their main secreted product, soluble-CD40-Ligand
por: Damien, Pauline, et al.
Publicado: (2015)

Development of QSAR models to predict blood-brain barrier permeability
por: Faramarzi, Sadegh, et al.
Publicado: (2022)

Excess CD40L does not rescue anti-DNA B cells from clonal anergy
por: Aslam, Mohammad, et al.
Publicado: (2014)

Triggering CD40 on endothelial cells contributes to tumor growth
por: Chiodoni, Claudia, et al.
Publicado: (2006)

Frog Virus 3 dissemination in the brain of tadpoles, but not in adult Xenopus, involves blood brain barrier dysfunction
por: De Jesús Andino, Francisco, et al.
Publicado: (2016)

The Soluble Factor from Oral Cancer Cell Lines Inhibits Interferon-γ Production by OK-432 via the CD40/CD40 Ligand Pathway
por: Ohe, Go, et al.
Publicado: (2021)

The permeability barrier in mammalian epidermis
Publicado: (1975)

Association between serum soluble CD40 ligand levels and mortality in patients with severe sepsis
por: Lorente, Leonardo, et al.
Publicado: (2011)

The Serum Levels of the Soluble Factors sCD40L and CXCL1 Are Not Indicative of Endometriosis
por: Pateisky, Petra, et al.
Publicado: (2016)

Serum immune checkpoint profiling identifies soluble CD40 as a biomarker for pancreatic cancer
por: Digomann, David, et al.
Publicado: (2023)

Macrophages and Fc-receptor interactions contribute to the antitumour activities of the anti-CD40 antibody SGN-40
por: Oflazoglu, E, et al.
Publicado: (2009)

CD40–CD40L in Neurological Disease
por: Ots, Heather D., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_te5pd2b358hfdjh8696u0rf25m