Serum Starvation Induces DRAM Expression in Liver Cancer Cells via Histone Modifications within Its Promoter Locus

DRAM is a lysosomal membrane protein and is critical for p53-mediated autophagy and apoptosis. DRAM has a potential tumor-suppressive function and is downregulated in many human cancers. However, the regulation of DRAM expression is poorly described so far. Here, we demonstrated that serum deprivati...

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Detalles Bibliográficos
Autores principales: Ni, Peihua, Xu, Hong, Chen, Changqiang, Wang, Jiayi, Liu, Xiangfan, Hu, Yiqun, Fan, Qishi, Hou, Zhaoyuan, Lu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520922/
https://www.ncbi.nlm.nih.gov/pubmed/23251372
http://dx.doi.org/10.1371/journal.pone.0050502

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