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Surface Microstructures on Planar Substrates and Textile Fibers Guide Neurite Outgrowth: A Scaffold Solution to Push Limits of Critical Nerve Defect Regeneration?

The treatment of critical size peripheral nerve defects represents one of the most serious problems in neurosurgery. If the gap size exceeds a certain limit, healing can't be achieved. Connection mismatching may further reduce the clinical success. The present study investigates how far specifi...

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Detalles Bibliográficos
Autores principales: Weigel, Stefan, Osterwalder, Thomas, Tobler, Ursina, Yao, Li, Wiesli, Manuel, Lehnert, Thomas, Pandit, Abhay, Bruinink, Arie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520951/
https://www.ncbi.nlm.nih.gov/pubmed/23251379
http://dx.doi.org/10.1371/journal.pone.0050714

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