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Transduction of Skeletal Muscles with Common Reporter Genes Can Promote Muscle Fiber Degeneration and Inflammation

Recombinant adeno-associated viral vectors (rAAV vectors) are promising tools for delivering transgenes to skeletal muscle, in order to study the mechanisms that control the muscle phenotype, and to ameliorate diseases that perturb muscle homeostasis. Many studies have employed rAAV vectors carrying...

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Detalles Bibliográficos
Autores principales: Winbanks, Catherine E., Beyer, Claudia, Qian, Hongwei, Gregorevic, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520959/
https://www.ncbi.nlm.nih.gov/pubmed/23251598
http://dx.doi.org/10.1371/journal.pone.0051627