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Finding Missing Heritability in Less Significant Loci and Allelic Heterogeneity: Genetic Variation in Human Height
Genome-wide association studies (GWAS) have identified many common variants associated with complex traits in human populations. Thus far, most reported variants have relatively small effects and explain only a small proportion of phenotypic variance, leading to the issues of ‘missing’ heritability...
Autores principales: | Zhang, Ge, Karns, Rebekah, Sun, Guangyun, Indugula, Subba Rao, Cheng, Hong, Havas-Augustin, Dubravka, Novokmet, Natalija, Durakovic, Zijad, Missoni, Sasa, Chakraborty, Ranajit, Rudan, Pavao, Deka, Ranjan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521016/ https://www.ncbi.nlm.nih.gov/pubmed/23251454 http://dx.doi.org/10.1371/journal.pone.0051211 |
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