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G1/S Cell Cycle Checkpoint Defect in Lymphocytes from Patients with Alzheimer's Disease

OBJECTIVE: We compared the cell responsiveness of activated lymphocytes to rapamycin, which blocks the G1/S transition, between patients with Alzheimer's disease (AD) and normal controls to assess the early phase control defect in cell cycle. METHODS: Blood samples of 26 patients with AD and 28...

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Detalles Bibliográficos
Autores principales: Song, Misun, Kwon, Young-Ah, Lee, Yujin, Kim, Hyeran, Yun, Ji Hea, Kim, Seonwoo, Kim, Doh Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neuropsychiatric Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521120/
https://www.ncbi.nlm.nih.gov/pubmed/23251208
http://dx.doi.org/10.4306/pi.2012.9.4.413