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Plasmodium serine hydroxymethyltransferase: indispensability and display of distinct localization

BACKGROUND: Serine hydroxymethyltransferase (SHMT), a pyridoxal phosphate-dependent enzyme, plays a vital role in the de novo pyrimidine biosynthesis pathway in malaria parasites. Two genes have been identified in Plasmodium spp. encoding a cytosolic SHMT (cSHMT) and putative mitochondria SHMT (mSHM...

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Detalles Bibliográficos
Autores principales:	Pornthanakasem, Wichai, Kongkasuriyachai, Darin, Uthaipibull, Chairat, Yuthavong, Yongyuth, Leartsakulpanich, Ubolsree
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521198/ https://www.ncbi.nlm.nih.gov/pubmed/23173711 http://dx.doi.org/10.1186/1475-2875-11-387

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