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Consequences of phosphoenolpyruvate:sugar phosphotranferase system and pyruvate kinase isozymes inactivation in central carbon metabolism flux distribution in Escherichia coli

BACKGROUND: In Escherichia coli phosphoenolpyruvate (PEP) is a key central metabolism intermediate that participates in glucose transport, as precursor in several biosynthetic pathways and it is involved in allosteric regulation of glycolytic enzymes. In this work we generated W3110 derivative strai...

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Detalles Bibliográficos
Autores principales: Meza, Eugenio, Becker, Judith, Bolivar, Francisco, Gosset, Guillermo, Wittmann, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521201/
https://www.ncbi.nlm.nih.gov/pubmed/22973998
http://dx.doi.org/10.1186/1475-2859-11-127

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