A structurally informed autotransporter platform for efficient heterologous protein secretion and display

BACKGROUND: The self-sufficient autotransporter (AT) pathway, ubiquitous in Gram-negative bacteria, combines a relatively simple protein secretion mechanism with a high transport capacity. ATs consist of a secreted passenger domain and a β-domain that facilitates transfer of the passenger across the...

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Detalles Bibliográficos
Autores principales: Jong, Wouter SP, Soprova, Zora, de Punder, Karin, ten Hagen-Jongman, Corinne M, Wagner, Samuel, Wickström, David, de Gier, Jan-Willem, Andersen, Peter, van der Wel, Nicole N, Luirink, Joen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521207/
https://www.ncbi.nlm.nih.gov/pubmed/22709508
http://dx.doi.org/10.1186/1475-2859-11-85

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