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A computational tool for the design of live attenuated virus vaccine based on microRNA-mediated gene silencing

BACKGROUND: The microRNA-based gene-silencing machinery has been recognized as a promising approach to control viral replication and used for improving safety for the live attenuated virus vaccines. The effective host microRNA response elements (MREs) have been incorporated into a virus sequence mai...

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Detalles Bibliográficos
Autores principales:	Wichadakul, Duangdao, Mhuantong, Wuttichai, Jongkaewwattana, Anan, Ingsriswang, Supawadee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521223/ https://www.ncbi.nlm.nih.gov/pubmed/23281624 http://dx.doi.org/10.1186/1471-2164-13-S7-S15

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