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Simultaneous amplitude-contrast and phase-contrast surface plasmon resonance imaging by use of digital holography
The surface plasmon resonance imaging technique provides a tool that allows high-throughput analysis and real-time kinetic measurement. A simultaneous amplitude-contrast and phase-contrast surface plasmon resonance imaging method is presented. The amplitude-contrast and phase-contrast images are sim...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Optical Society of America
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521296/ https://www.ncbi.nlm.nih.gov/pubmed/23243569 http://dx.doi.org/10.1364/BOE.3.003190 |
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author | Li, Shiping Zhong, Jingang |
author_facet | Li, Shiping Zhong, Jingang |
author_sort | Li, Shiping |
collection | PubMed |
description | The surface plasmon resonance imaging technique provides a tool that allows high-throughput analysis and real-time kinetic measurement. A simultaneous amplitude-contrast and phase-contrast surface plasmon resonance imaging method is presented. The amplitude-contrast and phase-contrast images are simultaneously obtained by use of digital holography. The detection sensitivity of amplitude-contrast imaging and phase-contrast imaging can compensate for each other. Thus, the detectable sample components may cover a wider range of refractive index values for the simultaneous amplitude-contrast and phase-contrast imaging method than for the phase-contrast imaging method or amplitude-contrast imaging method. A detailed description of the theory and an experiment of monitoring the evaporation process of a drop of NaCl injection in real time are presented. In addition, the amplitude-contrast image has less coherent noise by digital holography. |
format | Online Article Text |
id | pubmed-3521296 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Optical Society of America |
record_format | MEDLINE/PubMed |
spelling | pubmed-35212962012-12-14 Simultaneous amplitude-contrast and phase-contrast surface plasmon resonance imaging by use of digital holography Li, Shiping Zhong, Jingang Biomed Opt Express Biosensors and Molecular Diagnostics The surface plasmon resonance imaging technique provides a tool that allows high-throughput analysis and real-time kinetic measurement. A simultaneous amplitude-contrast and phase-contrast surface plasmon resonance imaging method is presented. The amplitude-contrast and phase-contrast images are simultaneously obtained by use of digital holography. The detection sensitivity of amplitude-contrast imaging and phase-contrast imaging can compensate for each other. Thus, the detectable sample components may cover a wider range of refractive index values for the simultaneous amplitude-contrast and phase-contrast imaging method than for the phase-contrast imaging method or amplitude-contrast imaging method. A detailed description of the theory and an experiment of monitoring the evaporation process of a drop of NaCl injection in real time are presented. In addition, the amplitude-contrast image has less coherent noise by digital holography. Optical Society of America 2012-11-08 /pmc/articles/PMC3521296/ /pubmed/23243569 http://dx.doi.org/10.1364/BOE.3.003190 Text en ©2012 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially. |
spellingShingle | Biosensors and Molecular Diagnostics Li, Shiping Zhong, Jingang Simultaneous amplitude-contrast and phase-contrast surface plasmon resonance imaging by use of digital holography |
title | Simultaneous amplitude-contrast and phase-contrast surface plasmon resonance imaging by use of digital holography |
title_full | Simultaneous amplitude-contrast and phase-contrast surface plasmon resonance imaging by use of digital holography |
title_fullStr | Simultaneous amplitude-contrast and phase-contrast surface plasmon resonance imaging by use of digital holography |
title_full_unstemmed | Simultaneous amplitude-contrast and phase-contrast surface plasmon resonance imaging by use of digital holography |
title_short | Simultaneous amplitude-contrast and phase-contrast surface plasmon resonance imaging by use of digital holography |
title_sort | simultaneous amplitude-contrast and phase-contrast surface plasmon resonance imaging by use of digital holography |
topic | Biosensors and Molecular Diagnostics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521296/ https://www.ncbi.nlm.nih.gov/pubmed/23243569 http://dx.doi.org/10.1364/BOE.3.003190 |
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