T lymphocyte apoptosis in asthma

The paper describes the possible role of apoptosis of T lymphocytes in asthma pathogenesis. The authors focused on resistance against Fas-mediated programed cell death and the role of Bcl-2 protein in impaired programed cell death process. The reports from the literature regarding the imbalance of T...

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Detalles Bibliográficos
Autores principales: Potapinska, O, Demkow, U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521346/
https://www.ncbi.nlm.nih.gov/pubmed/20156755
http://dx.doi.org/10.1186/2047-783X-14-S4-192
Descripción
Sumario:The paper describes the possible role of apoptosis of T lymphocytes in asthma pathogenesis. The authors focused on resistance against Fas-mediated programed cell death and the role of Bcl-2 protein in impaired programed cell death process. The reports from the literature regarding the imbalance of Th1 and Th2, caused by impaired apoptosis of T cells, in asthma pathogenesis are reviewed.

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