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Quantitative assessment of mitochondrial DNA copies from whole genome sequencing

BACKGROUND: Mitochondrial dysfunction is associated with various aging diseases. The copy number of mtDNA in human cells may therefore be a potential biomarker for diagnostics of aging. Here we propose a new computational method for the accurate assessment of mtDNA copies from whole genome sequencin...

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Detalles Bibliográficos
Autores principales:	Chu, Hsueh-Ting, Hsiao, William WL, Tsao, Theresa TH, Chang, Ching-Mao, Liu, Yen-Wenn, Fan, Chen-Chieh, Lin, Han, Chang, Hen-Hong, Yeh, Tze-Jung, Chen, Jen-Chih, Huang, Dun-Ming, Chen, Chaur-Chin, Kao, Cheng-Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521385/ https://www.ncbi.nlm.nih.gov/pubmed/23282223 http://dx.doi.org/10.1186/1471-2164-13-S7-S5

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