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A Novel Method for Real-Time, Continuous, Fluorescence-Based Analysis of Anti-DNA Abzyme Activity in Systemic Lupus

Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by the production of antibodies against a variety of self-antigens including nucleic acids. These antibodies are cytotoxic, catalytic (hydrolyzing DNA, RNA, and protein), and nephritogenic. Current methods for investigating ca...

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Detalles Bibliográficos
Autores principales: Cavallo, Michelle F., Kats, Anna M., Chen, Ran, Hartmann, James X., Pavlovic, Mirjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521466/
https://www.ncbi.nlm.nih.gov/pubmed/23251791
http://dx.doi.org/10.1155/2012/814048