Nonfunction of the ECT2 gene may cause renal tubulointerstitial injury leading to focal segmental glomerulosclerosis

BACKGROUND: Secondary focal segmental glomerulosclerosis (FSGS) follows congenital or acquired tubulointerstitial alterations such as in Dent’s disease, Lowe syndrome, and reflux nephropathy. Failure of adequate regeneration after tubulointerstitial injury, or abnormal tubulogenesis, can disturb int...

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Detalles Bibliográficos
Autores principales: Izu, Akane, Sugimoto, Keisuke, Fujita, Shinsuke, Nishi, Hitomi, Takemura, Yutaka, Okada, Mitsuru, Takemura, Tsukasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521645/
https://www.ncbi.nlm.nih.gov/pubmed/22552385
http://dx.doi.org/10.1007/s10157-012-0636-0

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