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Tuning Promoter Strength through RNA Polymerase Binding Site Design in Escherichia coli
One of the paramount goals of synthetic biology is to have the ability to tune transcriptional networks to targeted levels of expression at will. As a step in that direction, we have constructed a set of [Image: see text] unique binding sites for E. coli RNA Polymerase (RNAP) [Image: see text] holoe...
Autores principales: | Brewster, Robert C., Jones, Daniel L., Phillips, Rob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521663/ https://www.ncbi.nlm.nih.gov/pubmed/23271961 http://dx.doi.org/10.1371/journal.pcbi.1002811 |
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