Cargando…
The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle
Microtubule dynamics are essential throughout mitosis to ensure correct chromosome segregation. Microtubule depolymerization is controlled in part by microtubule depolymerases, including the kinesin-13 family of proteins. In humans, there are three closely related kinesin-13 isoforms (Kif2a, Kif2b,...
Autores principales: | Welburn, Julie P. I., Cheeseman, Iain M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521686/ https://www.ncbi.nlm.nih.gov/pubmed/23087211 http://dx.doi.org/10.1091/mbc.E12-03-0214 |
Ejemplares similares
-
DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement
por: Jang, Chang-Young, et al.
Publicado: (2008) -
Microtubule end tethering of a processive kinesin-8 motor Kif18b is required for spindle positioning
por: McHugh, Toni, et al.
Publicado: (2018) -
Small molecule allosteric uncoupling of microtubule depolymerase activity from motility in human Kinesin-5 during mitotic spindle assembly
por: Kim, Catherine D., et al.
Publicado: (2019) -
Expression Levels of a Kinesin-13 Microtubule Depolymerase Modulates the Effectiveness of Anti-Microtubule Agents
por: Schimizzi, Gregory V., et al.
Publicado: (2010) -
A Non-Motor Microtubule Binding Site Is Essential for the High Processivity and Mitotic Function of Kinesin-8 Kif18A
por: Mayr, Monika I., et al.
Publicado: (2011)