Cargando…
A Genome-Wide RNAi Screen Reveals MAP Kinase Phosphatases as Key ERK Pathway Regulators during Embryonic Stem Cell Differentiation
Embryonic stem cells and induced pluripotent stem cells represent potentially important therapeutic agents in regenerative medicine. Complex interlinked transcriptional and signaling networks control the fate of these cells towards maintenance of pluripotency or differentiation. In this study we hav...
Autores principales: | Yang, Shen-Hsi, Kalkan, Tuzer, Morrisroe, Claire, Smith, Austin, Sharrocks, Andrew D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521700/ https://www.ncbi.nlm.nih.gov/pubmed/23271975 http://dx.doi.org/10.1371/journal.pgen.1003112 |
Ejemplares similares
-
Otx2 and Oct4 Drive Early Enhancer Activation during Embryonic Stem Cell Transition from Naive Pluripotency
por: Yang, Shen-Hsi, et al.
Publicado: (2014) -
Mapping the route from naive pluripotency to lineage specification
por: Kalkan, Tüzer, et al.
Publicado: (2014) -
NODAL Secures Pluripotency upon Embryonic Stem Cell Progression from the Ground State
por: Mulas, Carla, et al.
Publicado: (2017) -
The Ubiquitin Ligase UBE3A Dampens ERK Pathway Signalling in HPV E6 Transformed HeLa Cells
por: Aguilar-Martinez, Elisa, et al.
Publicado: (2015) -
Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation
por: Wray, Jason, et al.
Publicado: (2011)