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A Genome-Wide RNAi Screen Reveals MAP Kinase Phosphatases as Key ERK Pathway Regulators during Embryonic Stem Cell Differentiation

Embryonic stem cells and induced pluripotent stem cells represent potentially important therapeutic agents in regenerative medicine. Complex interlinked transcriptional and signaling networks control the fate of these cells towards maintenance of pluripotency or differentiation. In this study we hav...

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Detalles Bibliográficos
Autores principales: Yang, Shen-Hsi, Kalkan, Tuzer, Morrisroe, Claire, Smith, Austin, Sharrocks, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521700/
https://www.ncbi.nlm.nih.gov/pubmed/23271975
http://dx.doi.org/10.1371/journal.pgen.1003112

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