Cargando…
Hypoxia-Induced Aggressiveness of Pancreatic Cancer Cells Is Due to Increased Expression of VEGF, IL-6 and miR-21, Which Can Be Attenuated by CDF Treatment
Hypoxia is known to play critical roles in cell survival, angiogenesis, tumor invasion, and metastasis. Hypoxia mediated over-expression of hypoxia-inducible factor (HIF) has been shown to be associated with therapeutic resistance, and contributes to poor prognosis of cancer patients. Emerging evide...
Autores principales: | Bao, Bin, Ali, Shadan, Ahmad, Aamir, Azmi, Asfar S., Li, Yiwei, Banerjee, Sanjeev, Kong, Dejuan, Sethi, Seema, Aboukameel, Amro, Padhye, Subhash B., Sarkar, Fazlul H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521759/ https://www.ncbi.nlm.nih.gov/pubmed/23272057 http://dx.doi.org/10.1371/journal.pone.0050165 |
Ejemplares similares
-
Hypoxia Induced Aggressiveness of Prostate Cancer Cells Is Linked with Deregulated Expression of VEGF, IL-6 and miRNAs That Are Attenuated by CDF
por: Bao, Bin, et al.
Publicado: (2012) -
Anti-Tumor Activity of a Novel Compound-CDF Is Mediated by Regulating miR-21, miR-200, and PTEN in Pancreatic Cancer
por: Bao, Bin, et al.
Publicado: (2011) -
Epithelial to Mesenchymal Transition Is Mechanistically Linked with Stem Cell Signatures in Prostate Cancer Cells
por: Kong, Dejuan, et al.
Publicado: (2010) -
Activated K-ras and INK4a/Arf Deficiency Cooperate During the Development of Pancreatic Cancer by Activation of Notch and NF-κB Signaling Pathways
por: Wang, Zhiwei, et al.
Publicado: (2011) -
Difluorinated-Curcumin (CDF) Restores PTEN Expression in Colon Cancer Cells by Down-Regulating miR-21
por: Roy, Sanchita, et al.
Publicado: (2013)