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Dexamethasone Regulates CFTR Expression in Calu-3 Cells with the Involvement of Chaperones HSP70 and HSP90

BACKGROUND: Dexamethasone is widely used for pulmonary exacerbation in patients with cystic fibrosis, however, not much is known about the effects of glucocorticoids on the wild-type cystic fibrosis channel transmembrane regulator (CFTR). Our aim was to determine the effects of dexamethasone treatme...

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Detalles Bibliográficos
Autores principales: Prota, Luiz Felipe M., Cebotaru, Liudmila, Cheng, Jie, Wright, Jerry, Vij, Neeraj, Morales, Marcelo M., Guggino, William B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521767/
https://www.ncbi.nlm.nih.gov/pubmed/23272037
http://dx.doi.org/10.1371/journal.pone.0047405