Cargando…

Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability

The innate immune response is essential for combating infectious disease. Macrophages and other cells respond to infection by releasing cytokines such as interleukin-1β (IL-1β), which in turn activate a well-described myeloid differentiation factor 88 (MYD88) -mediated, nuclear factor-κB (NF-κB) -de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Weiquan, London, Nyall R., Gibson, Christopher C., Davis, Chadwick T., Tong, Zongzhong, Sorensen, Lise K., Shi, Dallas S., Guo, Jinping, Smith, Matthew C. P., Grossmann, Allie H., Thomas, Kirk R., Li, Dean Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521847/ https://www.ncbi.nlm.nih.gov/pubmed/23143332 http://dx.doi.org/10.1038/nature11603

Ejemplares similares

The Guanine Nucleotide Exchange Factor ARNO mediates the activation of ARF and phospholipase D by insulin
por: Li, Hai-Sheng, et al.
Publicado: (2003)

Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO
por: Rafiq, Nisha Bte Mohd, et al.
Publicado: (2017)

Arf6 Can Trigger Wave Regulatory Complex-Dependent Actin Assembly Independent of Arno
por: Singh, Vikash, et al.
Publicado: (2020)

ARNO is recruited by the neuronal adaptor FE65 to potentiate ARF6-mediated neurite outgrowth
por: Zhai, Yuqi, et al.
Publicado: (2022)

An interview with Arno Locks
por: Derech, Carla D’Agostini, et al.
Publicado: (2014)

GRASP and IPCEF Promote ARF-to-Rac Signaling and Cell Migration by Coordinating the Association of ARNO/cytohesin 2 with Dock180
por: White, David T., et al.
Publicado: (2010)

ARNO gets things moving
por: Dove, Alan W.
Publicado: (2001)

Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D
por: Santy, Lorraine C., et al.
Publicado: (2001)

V-ATPase modulates exocytosis in neuroendocrine cells through the activation of the ARNO-Arf6-PLD pathway and the synthesis of phosphatidic acid
por: Wang, Qili, et al.
Publicado: (2023)

ARF-GEF cytohesin-2/ARNO regulates R-Ras and α5-integrin recycling through an EHD1-positive compartment
por: Salem, Joseph C., et al.
Publicado: (2015)

Cytohesins/ARNO: The Function in Colorectal Cancer Cells
por: Pan, Tao, et al.
Publicado: (2014)

MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18
por: Salcedo, Rosalba, et al.
Publicado: (2010)

SYK is activated by mutated MYD88 and drives pro-survival signaling in MYD88 driven B-cell lymphomas
por: Munshi, Manit, et al.
Publicado: (2020)

MyD88 and beyond: a perspective on MyD88-targeted therapeutic approach for modulation of host immunity
por: Saikh, Kamal U.
Publicado: (2021)

Schisandrin B Attenuates Diabetic Cardiomyopathy by Targeting MyD88 and Inhibiting MyD88‐Dependent Inflammation
por: Luo, Wu, et al.
Publicado: (2022)

A MyD88 meddles with survival
por: Bashyam, Hema
Publicado: (2007)

Role of MyD88 in Adenovirus Keratitis
por: Zhou, Xiaohong, et al.
Publicado: (2016)

Correction: Cytohesins/ARNO: The Function in Colorectal Cancer Cells
por: Pan, Tao, et al.
Publicado: (2015)

Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts
por: Chen, Junbin, et al.
Publicado: (2020)

MyD88 deficiency aggravates the severity of acute pancreatitis by promoting MyD88-independent TRIF pathway-mediated necrosis
por: Yang, Du-Jiang, et al.
Publicado: (2022)

Myd88 Is Required for an Antibody Response to Retroviral Infection
por: Browne, Edward P., et al.
Publicado: (2009)

MyD88 contribution to ocular surface homeostasis
por: Reins, Rose Y., et al.
Publicado: (2017)

Mechanism of MyD88S mediated signal termination
por: Pustelny, Katarzyna, et al.
Publicado: (2022)

A Novel Kindred with MyD88 Deficiency
por: Bucciol, Giorgia, et al.
Publicado: (2022)

Identification and Function of Myeloid Differentiation Factor 88 (MyD88) in Litopenaeus vannamei
por: Zhang, Shuang, et al.
Publicado: (2012)

Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation
por: Livraghi-Butrico, Alessandra, et al.
Publicado: (2012)

Two Human MYD88 Variants, S34Y and R98C, Interfere with MyD88-IRAK4-Myddosome Assembly
por: George, Julie, et al.
Publicado: (2011)

Lipopolysaccharide Induces Inflammatory Hyperalgesia Triggering a TLR4/MyD88-Dependent Cytokine Cascade in the Mice Paw
por: Calil, Igor L., et al.
Publicado: (2014)

Myeloid Differentiation Factor 88 (MyD88)-Deficiency Increases Risk of Diabetes in Mice
por: Hosoi, Toru, et al.
Publicado: (2010)

MYD88 signals induce tumour-initiating cell generation through the NF-κB-HIF-1α activation cascade
por: Tanimura, Atsuko, et al.
Publicado: (2021)

Induction of IL-12p40 and type 1 immunity by Toxoplasma gondii in the absence of the TLR-MyD88 signaling cascade
por: Snyder, Lindsay M., et al.
Publicado: (2021)

Characterization analysis and polymorphism detection of the porcine Myd88 gene
por: Li, Xinyun, et al.
Publicado: (2009)

Toll-Like Receptors and Cancer: MYD88 Mutation and Inflammation
por: Wang, James Q., et al.
Publicado: (2014)

MyD88 Polymorphisms and Association with Susceptibility to Salmonella Pullorum
por: Liu, Xian-Qing, et al.
Publicado: (2015)

Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88
por: Sakai, Jiro, et al.
Publicado: (2017)

MYD88(L265P) and MYD88(other) variants show different molecular characteristics and prognostic significance in diffuse large B-cell lymphoma
por: Qin, Yan, et al.
Publicado: (2023)

INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling
por: Luong, Phi, et al.
Publicado: (2018)

Blockade of Myd88 signaling by a novel MyD88 inhibitor prevents colitis-associated colorectal cancer development by impairing myeloid-derived suppressor cells
por: Wang, Lu, et al.
Publicado: (2022)

An Arf/Rab cascade controls the growth and invasiveness of glioblastoma
por: Kulasekaran, Gopinath, et al.
Publicado: (2021)

Baicalein ameliorates TNBS-induced colitis by suppressing TLR4/MyD88 signaling cascade and NLRP3 inflammasome activation in mice
por: Luo, Xiaoping, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_f6lqb4srv0cv7pt0ei35k9jqp8