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Asymmetric bioreduction of activated alkenes to industrially relevant optically active compounds
Ene-reductases from the ‘Old Yellow Enzyme’ family of flavoproteins catalyze the asymmetric reduction of various α,β-unsaturated compounds at the expense of a nicotinamide cofactor. They have been applied to the synthesis of valuable enantiopure products, including chiral building blocks with broad...
Autores principales: | Winkler, Christoph K., Tasnádi, Gábor, Clay, Dorina, Hall, Mélanie, Faber, Kurt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Publishers
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521962/ https://www.ncbi.nlm.nih.gov/pubmed/22498437 http://dx.doi.org/10.1016/j.jbiotec.2012.03.023 |
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