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In non-transplant patients with multiple myeloma, the pre-treatment level of clonotypic cells predicts event-free survival

BACKGROUND: In multiple myeloma (MM), the immunoglobulin heavy chain VDJ gene rearrangement is a unique clonotypic signature that identifies all members of the myeloma clone independent of morphology or phenotype. Each clonotypic MM cell has only one genomic copy of the rearranged IgH VDJ. METHODS:...

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Detalles Bibliográficos
Autores principales:	Thulien, Kyle J, Belch, Andrew R, Reiman, Tony, Pilarski, Linda M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522007/ https://www.ncbi.nlm.nih.gov/pubmed/23083101 http://dx.doi.org/10.1186/1476-4598-11-78

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