Screening of Finnish RAD51C founder mutations in prostate and colorectal cancer patients

BACKGROUND: Rare, heterozygous germline mutations in the RAD51C gene have been found in breast and ovarian cancer families. In the Finnish population, we have identified two founder mutations in RAD51C that increase the risk of ovarian cancer but not breast cancer in the absence of ovarian cancer. R...

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Detalles Bibliográficos
Autores principales: Pelttari, Liisa M, Nurminen, Riikka, Gylfe, Alexandra, Aaltonen, Lauri A, Schleutker, Johanna, Nevanlinna, Heli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522023/
https://www.ncbi.nlm.nih.gov/pubmed/23176254
http://dx.doi.org/10.1186/1471-2407-12-552

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