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Simultaneous modulation of the intrinsic and extrinsic pathways by simvastatin in mediating prostate cancer cell apoptosis

BACKGROUND: Recent studies suggest the potential benefits of statins as anti-cancer agents. Mechanisms by which statins induce apoptosis in cancer cells are not clear. We previously showed that simvastatin inhibit prostate cancer cell functions and tumor growth. Molecular mechanisms by which simvast...

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Detalles Bibliográficos
Autores principales:	Goc, Anna, Kochuparambil, Samith T, Al-Husein, Belal, Al-Azayzih, Ahmad, Mohammad, Shuaib, Somanath, Payaningal R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522038/ https://www.ncbi.nlm.nih.gov/pubmed/22974127 http://dx.doi.org/10.1186/1471-2407-12-409

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