Neutrophils cast extracellular traps in response to protozoan parasites

Release of extracellular traps by neutrophils is a now well-established phenomenon that contributes to the innate response to extracellular bacterial and fungal pathogens. The importance of NETs during protozoan infection has been less explored, but recent findings suggest an emerging role for relea...

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Detalles Bibliográficos
Autores principales: Abdallah, Delbert S. Abi, Denkers, Eric Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522045/
https://www.ncbi.nlm.nih.gov/pubmed/23248631
http://dx.doi.org/10.3389/fimmu.2012.00382
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author Abdallah, Delbert S. Abi
Denkers, Eric Y.
author_facet Abdallah, Delbert S. Abi
Denkers, Eric Y.
author_sort Abdallah, Delbert S. Abi
collection PubMed
description Release of extracellular traps by neutrophils is a now well-established phenomenon that contributes to the innate response to extracellular bacterial and fungal pathogens. The importance of NETs during protozoan infection has been less explored, but recent findings suggest an emerging role for release of neutrophil-derived extracellular DNA in response to this class of microbial pathogens. The present review summarizes findings to date regarding elicitation of NETs by Toxoplasma gondii, Plasmodium falciparum, Eimeria bovis, and Leishmania spp.
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spelling pubmed-35220452012-12-17 Neutrophils cast extracellular traps in response to protozoan parasites Abdallah, Delbert S. Abi Denkers, Eric Y. Front Immunol Immunology Release of extracellular traps by neutrophils is a now well-established phenomenon that contributes to the innate response to extracellular bacterial and fungal pathogens. The importance of NETs during protozoan infection has been less explored, but recent findings suggest an emerging role for release of neutrophil-derived extracellular DNA in response to this class of microbial pathogens. The present review summarizes findings to date regarding elicitation of NETs by Toxoplasma gondii, Plasmodium falciparum, Eimeria bovis, and Leishmania spp. Frontiers Media S.A. 2012-12-14 /pmc/articles/PMC3522045/ /pubmed/23248631 http://dx.doi.org/10.3389/fimmu.2012.00382 Text en Copyright © Abi Abdallah and Denkers. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc
spellingShingle Immunology
Abdallah, Delbert S. Abi
Denkers, Eric Y.
Neutrophils cast extracellular traps in response to protozoan parasites
title Neutrophils cast extracellular traps in response to protozoan parasites
title_full Neutrophils cast extracellular traps in response to protozoan parasites
title_fullStr Neutrophils cast extracellular traps in response to protozoan parasites
title_full_unstemmed Neutrophils cast extracellular traps in response to protozoan parasites
title_short Neutrophils cast extracellular traps in response to protozoan parasites
title_sort neutrophils cast extracellular traps in response to protozoan parasites
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522045/
https://www.ncbi.nlm.nih.gov/pubmed/23248631
http://dx.doi.org/10.3389/fimmu.2012.00382
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