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Association of HLA-DR1 with the allergic response to the major mugwort pollen allergen: molecular background
BACKGROUND: Mugwort pollen allergens represent the main cause of pollinosis in late summer. The major allergen, Art v 1, contains only one single immunodominant, solely HLA-DR-restricted T cell epitope (Art v 1(25-36)). The frequency of HLA-DRB1*01 is highly increased in mugwort-allergic individuals...
Autores principales: | Knapp, Bernhard, Fischer, Gottfried, Van Hemelen, Dries, Fae, Ingrid, Maillere, Bernard, Ebner, Christof, Schreiner, Wolfgang, Bohle, Barbara, Jahn-Schmid, Beatrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522052/ https://www.ncbi.nlm.nih.gov/pubmed/22871092 http://dx.doi.org/10.1186/1471-2172-13-43 |
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