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Increased frequency of single base substitutions in a population of transcripts expressed in cancer cells
BACKGROUND: Single Base Substitutions (SBS) that alter transcripts expressed in cancer originate from somatic mutations. However, recent studies report SBS in transcripts that are not supported by the genomic DNA of tumor cells. METHODS: We used sequence based whole genome expression profiling, name...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522053/ https://www.ncbi.nlm.nih.gov/pubmed/23137041 http://dx.doi.org/10.1186/1471-2407-12-509 |