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Increased frequency of single base substitutions in a population of transcripts expressed in cancer cells

BACKGROUND: Single Base Substitutions (SBS) that alter transcripts expressed in cancer originate from somatic mutations. However, recent studies report SBS in transcripts that are not supported by the genomic DNA of tumor cells. METHODS: We used sequence based whole genome expression profiling, name...

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Detalles Bibliográficos
Autores principales: Bianchetti, Laurent, Kieffer, David, Féderkeil, Rémi, Poch, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522053/
https://www.ncbi.nlm.nih.gov/pubmed/23137041
http://dx.doi.org/10.1186/1471-2407-12-509