Restoration of Topoisomerase 2 Function by Complementation of Defective Monomers in Drosophila

Type II topoisomerases are essential ATP-dependent homodimeric enzymes required for transcription, replication, and chromosome segregation. These proteins alter DNA topology by generating transient enzyme-linked double-strand breaks for passage of one DNA strand through another. The central role of...

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Detalles Bibliográficos
Autores principales: Hohl, Amber M., Thompson, Morgan, Soshnev, Alexey A., Wu, Jianhong, Morris, James, Hsieh, Tao-Shih, Wu, C.-ting, Geyer, Pamela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522162/
https://www.ncbi.nlm.nih.gov/pubmed/22923380
http://dx.doi.org/10.1534/genetics.112.144006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522162/
https://www.ncbi.nlm.nih.gov/pubmed/22923380
http://dx.doi.org/10.1534/genetics.112.144006

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