Cargando…
Diagnostic Accuracy of Sixty Four Multi-Slice CT Angiography in Assessment of Arterial Cut-Off and Run-Off in Comparison with Surgical Findings
BACKGROUND/OBJECTIVE: The accurate anatomic mapping and determination of the severity of arterial disease, an important health problem of the elderly, is of great significance. We aimed to determine the diagnostic value of 64-multislice CT angiography (MSCTA) in run-off and cut-off sites of arterial...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kowsar
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522320/ https://www.ncbi.nlm.nih.gov/pubmed/23329923 |
_version_ | 1782253053128212480 |
---|---|
author | Noaparast, M. Rabani, A. Karimian, F. Bodaghabadi, M. Aran, S. Mirsharifi, R. Jafarian, A. Vaezi, F. Ghanaati, H. |
author_facet | Noaparast, M. Rabani, A. Karimian, F. Bodaghabadi, M. Aran, S. Mirsharifi, R. Jafarian, A. Vaezi, F. Ghanaati, H. |
author_sort | Noaparast, M. |
collection | PubMed |
description | BACKGROUND/OBJECTIVE: The accurate anatomic mapping and determination of the severity of arterial disease, an important health problem of the elderly, is of great significance. We aimed to determine the diagnostic value of 64-multislice CT angiography (MSCTA) in run-off and cut-off sites of arterial disease. PATIENTS AND METHODS: Throughout the study, MSCTA followed by an operative intervention was carried out on a total of 38 patients with clinical signs and symptoms suggestive of arterial disease (AD) all of whom had the indication for vascular surgery. The mean age of patients was 34±15.86 (range, 23 to 93) years. MSCTA was executed using a 64-slice CT scanner, during the arterial phase of injecting the nonionic, contrast medium with a power injector at the rate of 5 ml/sec into the antecubital vein and exploration and revascularization of peripheral arterial disease was performed intraoperatively. RESULTS: Atherosclerosis and arterial disease, the most common causes of vascular occlusion, were more common in the lower extremities. According to MSCTA findings, the most frequent site of stenosis was the superficial femoral artery. Spearman’s correlation coefficient showed a high degree of agreement amongst the raters. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and the accuracy of MSCTA compared to surgery were 83.8%, 96%, 96.8%, 81.3% and 89%, respectively. MSCTA findings were compared with surgery as a standard of reference, which showed concordance in the majority of cases (81.6%). Cut-off sites were correctly identified by MSCTA in 97.3% of the patients and the most common sites of discordance were the run-off sites (18.2%). CONCLUSION: MSCTA angiography as a novel diagnostic modality may be a suitable alternative and a viable choice for routine clinical diagnosis. |
format | Online Article Text |
id | pubmed-3522320 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Kowsar |
record_format | MEDLINE/PubMed |
spelling | pubmed-35223202013-01-17 Diagnostic Accuracy of Sixty Four Multi-Slice CT Angiography in Assessment of Arterial Cut-Off and Run-Off in Comparison with Surgical Findings Noaparast, M. Rabani, A. Karimian, F. Bodaghabadi, M. Aran, S. Mirsharifi, R. Jafarian, A. Vaezi, F. Ghanaati, H. Iran J Radiol Vascular & Interventional Radiology BACKGROUND/OBJECTIVE: The accurate anatomic mapping and determination of the severity of arterial disease, an important health problem of the elderly, is of great significance. We aimed to determine the diagnostic value of 64-multislice CT angiography (MSCTA) in run-off and cut-off sites of arterial disease. PATIENTS AND METHODS: Throughout the study, MSCTA followed by an operative intervention was carried out on a total of 38 patients with clinical signs and symptoms suggestive of arterial disease (AD) all of whom had the indication for vascular surgery. The mean age of patients was 34±15.86 (range, 23 to 93) years. MSCTA was executed using a 64-slice CT scanner, during the arterial phase of injecting the nonionic, contrast medium with a power injector at the rate of 5 ml/sec into the antecubital vein and exploration and revascularization of peripheral arterial disease was performed intraoperatively. RESULTS: Atherosclerosis and arterial disease, the most common causes of vascular occlusion, were more common in the lower extremities. According to MSCTA findings, the most frequent site of stenosis was the superficial femoral artery. Spearman’s correlation coefficient showed a high degree of agreement amongst the raters. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and the accuracy of MSCTA compared to surgery were 83.8%, 96%, 96.8%, 81.3% and 89%, respectively. MSCTA findings were compared with surgery as a standard of reference, which showed concordance in the majority of cases (81.6%). Cut-off sites were correctly identified by MSCTA in 97.3% of the patients and the most common sites of discordance were the run-off sites (18.2%). CONCLUSION: MSCTA angiography as a novel diagnostic modality may be a suitable alternative and a viable choice for routine clinical diagnosis. Kowsar 2011-09 2011-09-25 /pmc/articles/PMC3522320/ /pubmed/23329923 Text en Copyright © 2011, Tehran University of Medical Sciences and Iranian Society of Radiology http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Vascular & Interventional Radiology Noaparast, M. Rabani, A. Karimian, F. Bodaghabadi, M. Aran, S. Mirsharifi, R. Jafarian, A. Vaezi, F. Ghanaati, H. Diagnostic Accuracy of Sixty Four Multi-Slice CT Angiography in Assessment of Arterial Cut-Off and Run-Off in Comparison with Surgical Findings |
title | Diagnostic Accuracy of Sixty Four Multi-Slice CT Angiography in Assessment of Arterial Cut-Off and Run-Off in Comparison with Surgical Findings |
title_full | Diagnostic Accuracy of Sixty Four Multi-Slice CT Angiography in Assessment of Arterial Cut-Off and Run-Off in Comparison with Surgical Findings |
title_fullStr | Diagnostic Accuracy of Sixty Four Multi-Slice CT Angiography in Assessment of Arterial Cut-Off and Run-Off in Comparison with Surgical Findings |
title_full_unstemmed | Diagnostic Accuracy of Sixty Four Multi-Slice CT Angiography in Assessment of Arterial Cut-Off and Run-Off in Comparison with Surgical Findings |
title_short | Diagnostic Accuracy of Sixty Four Multi-Slice CT Angiography in Assessment of Arterial Cut-Off and Run-Off in Comparison with Surgical Findings |
title_sort | diagnostic accuracy of sixty four multi-slice ct angiography in assessment of arterial cut-off and run-off in comparison with surgical findings |
topic | Vascular & Interventional Radiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522320/ https://www.ncbi.nlm.nih.gov/pubmed/23329923 |
work_keys_str_mv | AT noaparastm diagnosticaccuracyofsixtyfourmultislicectangiographyinassessmentofarterialcutoffandrunoffincomparisonwithsurgicalfindings AT rabania diagnosticaccuracyofsixtyfourmultislicectangiographyinassessmentofarterialcutoffandrunoffincomparisonwithsurgicalfindings AT karimianf diagnosticaccuracyofsixtyfourmultislicectangiographyinassessmentofarterialcutoffandrunoffincomparisonwithsurgicalfindings AT bodaghabadim diagnosticaccuracyofsixtyfourmultislicectangiographyinassessmentofarterialcutoffandrunoffincomparisonwithsurgicalfindings AT arans diagnosticaccuracyofsixtyfourmultislicectangiographyinassessmentofarterialcutoffandrunoffincomparisonwithsurgicalfindings AT mirsharifir diagnosticaccuracyofsixtyfourmultislicectangiographyinassessmentofarterialcutoffandrunoffincomparisonwithsurgicalfindings AT jafariana diagnosticaccuracyofsixtyfourmultislicectangiographyinassessmentofarterialcutoffandrunoffincomparisonwithsurgicalfindings AT vaezif diagnosticaccuracyofsixtyfourmultislicectangiographyinassessmentofarterialcutoffandrunoffincomparisonwithsurgicalfindings AT ghanaatih diagnosticaccuracyofsixtyfourmultislicectangiographyinassessmentofarterialcutoffandrunoffincomparisonwithsurgicalfindings |