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Diagnostic Accuracy of Transvaginal Sonography in the Detection of Uterine Abnormalities in Infertile Women
BACKGROUND: Accurate diagnosis of uterine abnormalities has become a core part of the fertility work-up. A variety of modalities can be used for the diagnosis of uterine abnormalities. OBJECTIVES: This study was designed to assess the diagnostic accuracy of transvaginal ultrasonography (TVS) in uter...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kowsar
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522369/ https://www.ncbi.nlm.nih.gov/pubmed/23329979 http://dx.doi.org/10.5812/iranjradiol.8063 |
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author | Niknejadi, Maryam Haghighi, Hadieh Ahmadi, Firoozeh Niknejad, Fatemeh Chehrazi, Mohammad Vosough, Ahmad Moenian, Deena |
author_facet | Niknejadi, Maryam Haghighi, Hadieh Ahmadi, Firoozeh Niknejad, Fatemeh Chehrazi, Mohammad Vosough, Ahmad Moenian, Deena |
author_sort | Niknejadi, Maryam |
collection | PubMed |
description | BACKGROUND: Accurate diagnosis of uterine abnormalities has become a core part of the fertility work-up. A variety of modalities can be used for the diagnosis of uterine abnormalities. OBJECTIVES: This study was designed to assess the diagnostic accuracy of transvaginal ultrasonography (TVS) in uterine pathologies of infertile patients using hysteroscopy as the gold standard. PATIENTS AND METHODS: This was a cross-sectional study carried out in the Department of Reproductive Imaging at Royan Institute from October 2007 to October 2008. In this study, the medical documents of 719 infertile women who were investigated with transvaginal ultrasound (TVS) and then hysteroscopy were reviewed. All women underwent hysteroscopy in the same cycle time after TVS. Seventy-six out of 719 patients were excluded from the study and 643 patients were studied. TVS was performed in the follicular phase after cessation of bleeding. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for TVS. Hysteroscopy served as the gold standard. RESULTS: The overall sensitivity, specificity, positive and negative predictive values for TVS in the diagnosis of uterine abnormality was 79%, 82%, 84% and 71%, respectively. The sensitivity and PPV of TVS in detection of polyp were 88.3% and 81.6%, respectively. These indices were 89.2% and 92.5%, respectively for fibroma, 67% and 98.3%, respectively for subseptated uterus and 90.9% and 100%, respectively for septated uterus. Adhesion and unicornuated uterus have the lowest sensitivity with a sensitivity of 35% and PPV of 57.1%. CONCLUSION: TVS is a cost-effective and non-invasive method for diagnosis of intrauterine lesions such as polyps, submucosal fibroids and septum. It is a valuable adjunctive to hysteroscopy with high accuracy for identification and characterization of intrauterine abnormalities. This may lead to a more precise surgery plan and performance. |
format | Online Article Text |
id | pubmed-3522369 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Kowsar |
record_format | MEDLINE/PubMed |
spelling | pubmed-35223692013-01-17 Diagnostic Accuracy of Transvaginal Sonography in the Detection of Uterine Abnormalities in Infertile Women Niknejadi, Maryam Haghighi, Hadieh Ahmadi, Firoozeh Niknejad, Fatemeh Chehrazi, Mohammad Vosough, Ahmad Moenian, Deena Iran J Radiol Urogenital Imaging & Contrast Media BACKGROUND: Accurate diagnosis of uterine abnormalities has become a core part of the fertility work-up. A variety of modalities can be used for the diagnosis of uterine abnormalities. OBJECTIVES: This study was designed to assess the diagnostic accuracy of transvaginal ultrasonography (TVS) in uterine pathologies of infertile patients using hysteroscopy as the gold standard. PATIENTS AND METHODS: This was a cross-sectional study carried out in the Department of Reproductive Imaging at Royan Institute from October 2007 to October 2008. In this study, the medical documents of 719 infertile women who were investigated with transvaginal ultrasound (TVS) and then hysteroscopy were reviewed. All women underwent hysteroscopy in the same cycle time after TVS. Seventy-six out of 719 patients were excluded from the study and 643 patients were studied. TVS was performed in the follicular phase after cessation of bleeding. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for TVS. Hysteroscopy served as the gold standard. RESULTS: The overall sensitivity, specificity, positive and negative predictive values for TVS in the diagnosis of uterine abnormality was 79%, 82%, 84% and 71%, respectively. The sensitivity and PPV of TVS in detection of polyp were 88.3% and 81.6%, respectively. These indices were 89.2% and 92.5%, respectively for fibroma, 67% and 98.3%, respectively for subseptated uterus and 90.9% and 100%, respectively for septated uterus. Adhesion and unicornuated uterus have the lowest sensitivity with a sensitivity of 35% and PPV of 57.1%. CONCLUSION: TVS is a cost-effective and non-invasive method for diagnosis of intrauterine lesions such as polyps, submucosal fibroids and septum. It is a valuable adjunctive to hysteroscopy with high accuracy for identification and characterization of intrauterine abnormalities. This may lead to a more precise surgery plan and performance. Kowsar 2012-09-17 2012-09 /pmc/articles/PMC3522369/ /pubmed/23329979 http://dx.doi.org/10.5812/iranjradiol.8063 Text en Copyright © 2012, Tehran University of Medical Sciences and Iranian Society of Radiology http://creativecommons.org/licenses/by/3/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Urogenital Imaging & Contrast Media Niknejadi, Maryam Haghighi, Hadieh Ahmadi, Firoozeh Niknejad, Fatemeh Chehrazi, Mohammad Vosough, Ahmad Moenian, Deena Diagnostic Accuracy of Transvaginal Sonography in the Detection of Uterine Abnormalities in Infertile Women |
title | Diagnostic Accuracy of Transvaginal Sonography in the Detection of Uterine Abnormalities in Infertile Women |
title_full | Diagnostic Accuracy of Transvaginal Sonography in the Detection of Uterine Abnormalities in Infertile Women |
title_fullStr | Diagnostic Accuracy of Transvaginal Sonography in the Detection of Uterine Abnormalities in Infertile Women |
title_full_unstemmed | Diagnostic Accuracy of Transvaginal Sonography in the Detection of Uterine Abnormalities in Infertile Women |
title_short | Diagnostic Accuracy of Transvaginal Sonography in the Detection of Uterine Abnormalities in Infertile Women |
title_sort | diagnostic accuracy of transvaginal sonography in the detection of uterine abnormalities in infertile women |
topic | Urogenital Imaging & Contrast Media |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522369/ https://www.ncbi.nlm.nih.gov/pubmed/23329979 http://dx.doi.org/10.5812/iranjradiol.8063 |
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