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Promoter analysis of the DHCR24 (3β-hydroxysterol Δ(24)-reductase) gene: characterization of SREBP (sterol-regulatoryelement-binding protein)-mediated activation

DHCR24 (3β-hydroxysterol Δ(24)-reductase) catalyses the reduction of the C-24 double bond of sterol intermediates during cholesterol biosynthesis. DHCR24 has also been involved in cell growth, senescence and cellular response to oncogenic and oxidative stress. Despite its important roles, little is...

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Detalles Bibliográficos
Autores principales: Daimiel, Lidia A., Fernández-Suárez, María E., Rodríguez-Acebes, Sara, Crespo, Lorena, Lasunción, Miguel A., Gómez-Coronado, Diego, Martínez-Botas, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522477/
https://www.ncbi.nlm.nih.gov/pubmed/23050906
http://dx.doi.org/10.1042/BSR20120095