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Promoter analysis of the DHCR24 (3β-hydroxysterol Δ(24)-reductase) gene: characterization of SREBP (sterol-regulatoryelement-binding protein)-mediated activation
DHCR24 (3β-hydroxysterol Δ(24)-reductase) catalyses the reduction of the C-24 double bond of sterol intermediates during cholesterol biosynthesis. DHCR24 has also been involved in cell growth, senescence and cellular response to oncogenic and oxidative stress. Despite its important roles, little is...
Autores principales: | Daimiel, Lidia A., Fernández-Suárez, María E., Rodríguez-Acebes, Sara, Crespo, Lorena, Lasunción, Miguel A., Gómez-Coronado, Diego, Martínez-Botas, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522477/ https://www.ncbi.nlm.nih.gov/pubmed/23050906 http://dx.doi.org/10.1042/BSR20120095 |
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