Cargando…
The severity of mammary gland developmental defects is linked to the overall functional status of Cx43 as revealed by genetically modified mice
Genetically modified mice mimicking ODDD (oculodentodigital dysplasia), a disease characterized by reduced Cx43 (connexin 43)-mediated gap junctional intercellular communication, represent an in vivo model to assess the role of Cx43 in mammary gland development and function. We previously reported t...
Autores principales: | Stewart, Michael K. G., Gong, Xiang-Qun, Barr, Kevin J., Bai, Donglin, Fishman, Glenn I., Laird, Dale W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522501/ https://www.ncbi.nlm.nih.gov/pubmed/23075222 http://dx.doi.org/10.1042/BJ20121070 |
Ejemplares similares
-
Structure and functional studies of N-terminal Cx43 mutants linked to oculodentodigital dysplasia
por: Shao, Qing, et al.
Publicado: (2012) -
Mammary Gland Specific Knockdown of the Physiological Surge in Cx26 during Lactation Retains Normal Mammary Gland Development and Function
por: Stewart, Michael K. G., et al.
Publicado: (2014) -
Comparative Analysis of Cx31 and Cx43 in Differentiation-Competent Rodent Keratinocytes
por: Au, Akina, et al.
Publicado: (2020) -
Cx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancer
por: Stewart, Michael K.G., et al.
Publicado: (2015) -
Specific functional pathologies of Cx43 mutations associated with oculodentodigital dysplasia
por: Kelly, John J., et al.
Publicado: (2016)