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Integrated QSAR study for inhibitors of hedgehog signal pathway against multiple cell lines:a collaborative filtering method

BACKGROUND: The Hedgehog Signaling Pathway is one of signaling pathways that are very important to embryonic development. The participation of inhibitors in the Hedgehog Signal Pathway can control cell growth and death, and searching novel inhibitors to the functioning of the pathway are in a great...

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Detalles Bibliográficos
Autores principales: Gao, Jun, Che, Dongsheng, Zheng, Vincent W, Zhu, Ruixin, Liu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522553/
https://www.ncbi.nlm.nih.gov/pubmed/22849868
http://dx.doi.org/10.1186/1471-2105-13-186