Salvinorin A reduces mechanical allodynia and spinal neuronal hyperexcitability induced by peripheral formalin injection

BACKGROUND: Salvinorin A (SA), the main active component of Salvia Divinorum, is a non-nitrogenous kappa opioid receptor (KOR) agonist. It has been shown to reduce acute pain and to exert potent antinflammatory effects. This study assesses the effects and the mode of action of SA on formalin-induced...

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Detalles Bibliográficos
Autores principales: Guida, Francesca, Luongo, Livio, Aviello, Gabriella, Palazzo, Enza, De Chiaro, Maria, Gatta, Luisa, Boccella, Serena, Marabese, Ida, Zjawiony, Jordan K, Capasso, Raffaele, Izzo, Angelo A, de Novellis, Vito, Maione, Sabatino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522567/
https://www.ncbi.nlm.nih.gov/pubmed/22913292
http://dx.doi.org/10.1186/1744-8069-8-60

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