Azurophil Granule Proteins Constitute the Major Mycobactericidal Proteins in Human Neutrophils and Enhance the Killing of Mycobacteria in Macrophages

Pathogenic mycobacteria reside in, and are in turn controlled by, macrophages. However, emerging data suggest that neutrophils also play a critical role in innate immunity to tuberculosis, presumably by their different antibacterial granule proteins. In this study, we purified neutrophil azurophil a...

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Detalles Bibliográficos
Autores principales: Jena, Prajna, Mohanty, Soumitra, Mohanty, Tirthankar, Kallert, Stephanie, Morgelin, Matthias, Lindstrøm, Thomas, Borregaard, Niels, Stenger, Steffen, Sonawane, Avinash, Sørensen, Ole E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522671/
https://www.ncbi.nlm.nih.gov/pubmed/23251364
http://dx.doi.org/10.1371/journal.pone.0050345

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