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Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

Innate immune sensing of viral nucleic acids triggers type I interferon (IFN) production, which activates interferon-stimulated genes (ISGs) and directs a multifaceted antiviral response. ISGs can also be activated through IFN-independent pathways, although the precise mechanisms remain elusive. Her...

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Detalles Bibliográficos
Autores principales:	Hasan, Maroof, Koch, James, Rakheja, Dinesh, Pattnaik, Asit K., Brugarolas, James, Dozmorov, Igor, Levine, Beth, Wakeland, Edward K., Lee-kirsch, Min Ae, Yan, Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522772/ https://www.ncbi.nlm.nih.gov/pubmed/23160154 http://dx.doi.org/10.1038/ni.2475

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