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Complex regulation controls Neurogenin3 proteolysis
The ubiquitin proteasome system (UPS) is known to be responsible for the rapid turnover of many transcription factors, where half-life is held to be critical for regulation of transcriptional activity. However, the stability of key transcriptional regulators of development is often very poorly chara...
Autores principales: | Roark, Ryan, Itzhaki, Laura, Philpott, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522888/ https://www.ncbi.nlm.nih.gov/pubmed/23259061 http://dx.doi.org/10.1242/bio.20121750 |
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