Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors

Whispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit(®)L100 coated microspherical WGMR as an efficient immunosensor. The de...

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Detalles Bibliográficos
Autores principales: Giannetti, Ambra, Berneschi, Simone, Baldini, Francesco, Cosi, Franco, Conti, Gualtiero Nunzi, Soria, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522931/
https://www.ncbi.nlm.nih.gov/pubmed/23202178
http://dx.doi.org/10.3390/s121114604
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author Giannetti, Ambra
Berneschi, Simone
Baldini, Francesco
Cosi, Franco
Conti, Gualtiero Nunzi
Soria, Silvia
author_facet Giannetti, Ambra
Berneschi, Simone
Baldini, Francesco
Cosi, Franco
Conti, Gualtiero Nunzi
Soria, Silvia
author_sort Giannetti, Ambra
collection PubMed
description Whispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit(®)L100 coated microspherical WGMR as an efficient immunosensor. The developed resonator was morphologically characterized using fluorescence microscopy. The functionalization process was tuned to preserve the high Q factor of the resonator. The protein binding assay was optically characterized in terms of specificity in buffer solution.
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spelling pubmed-35229312013-01-09 Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors Giannetti, Ambra Berneschi, Simone Baldini, Francesco Cosi, Franco Conti, Gualtiero Nunzi Soria, Silvia Sensors (Basel) Article Whispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit(®)L100 coated microspherical WGMR as an efficient immunosensor. The developed resonator was morphologically characterized using fluorescence microscopy. The functionalization process was tuned to preserve the high Q factor of the resonator. The protein binding assay was optically characterized in terms of specificity in buffer solution. Molecular Diversity Preservation International (MDPI) 2012-10-30 /pmc/articles/PMC3522931/ /pubmed/23202178 http://dx.doi.org/10.3390/s121114604 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Giannetti, Ambra
Berneschi, Simone
Baldini, Francesco
Cosi, Franco
Conti, Gualtiero Nunzi
Soria, Silvia
Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors
title Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors
title_full Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors
title_fullStr Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors
title_full_unstemmed Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors
title_short Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors
title_sort performance of eudragit coated whispering gallery mode resonator-based immunosensors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522931/
https://www.ncbi.nlm.nih.gov/pubmed/23202178
http://dx.doi.org/10.3390/s121114604
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