Individual differences and evidence-based psychopharmacology

Individual differences in response to pharmacologic treatment limits the usefulness of mean data obtained from randomized controlled trials. These individual differences exist even in genetically uniform inbred mouse strains. While stratification can be of value in large studies, the individual pati...

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Detalles Bibliográficos
Autores principales: Belmaker, RH, Bersudsky, Yuly, Agam, Galila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523057/
https://www.ncbi.nlm.nih.gov/pubmed/23016518
http://dx.doi.org/10.1186/1741-7015-10-110
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author Belmaker, RH
Bersudsky, Yuly
Agam, Galila
author_facet Belmaker, RH
Bersudsky, Yuly
Agam, Galila
author_sort Belmaker, RH
collection PubMed
description Individual differences in response to pharmacologic treatment limits the usefulness of mean data obtained from randomized controlled trials. These individual differences exist even in genetically uniform inbred mouse strains. While stratification can be of value in large studies, the individual patient history is the most effective currently available guide for personalized medicine in psychopharmacology.
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spelling pubmed-35230572012-12-16 Individual differences and evidence-based psychopharmacology Belmaker, RH Bersudsky, Yuly Agam, Galila BMC Med Commentary Individual differences in response to pharmacologic treatment limits the usefulness of mean data obtained from randomized controlled trials. These individual differences exist even in genetically uniform inbred mouse strains. While stratification can be of value in large studies, the individual patient history is the most effective currently available guide for personalized medicine in psychopharmacology. BioMed Central 2012-09-27 /pmc/articles/PMC3523057/ /pubmed/23016518 http://dx.doi.org/10.1186/1741-7015-10-110 Text en Copyright ©2012 Belmaker et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Belmaker, RH
Bersudsky, Yuly
Agam, Galila
Individual differences and evidence-based psychopharmacology
title Individual differences and evidence-based psychopharmacology
title_full Individual differences and evidence-based psychopharmacology
title_fullStr Individual differences and evidence-based psychopharmacology
title_full_unstemmed Individual differences and evidence-based psychopharmacology
title_short Individual differences and evidence-based psychopharmacology
title_sort individual differences and evidence-based psychopharmacology
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523057/
https://www.ncbi.nlm.nih.gov/pubmed/23016518
http://dx.doi.org/10.1186/1741-7015-10-110
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