Cargando…

Preclinical Alzheimer disease: identification of cases at risk among cognitively intact older individuals

Since the first description of the case of Auguste Deter, presented in Tübingen in 1906 by Alois Alzheimer, there has been an exponential increase in our knowledge of the neuropathological, cellular, and molecular foundation of Alzheimer's disease (AD). The concept of AD pathogenesis has evolve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lazarczyk, Maciej J, Hof, Patrick R, Bouras, Constantin, Giannakopoulos, Panteleimon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Opinion
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523068/ https://www.ncbi.nlm.nih.gov/pubmed/23098093 http://dx.doi.org/10.1186/1741-7015-10-127

Ejemplares similares

Heterozygous Chorein Deficiency in Probable Tau-negative Early-onset Alzheimer Disease
por: Lazarczyk, Maciej J., et al.
Publicado: (2016)

Is the time ripe for new diagnostic criteria of cognitive impairment due to cerebrovascular disease? Consensus report of the International Congress on Vascular Dementia working group
por: Perneczky, Robert, et al.
Publicado: (2016)

Selective acquired long QT syndrome (saLQTS) upon risperidone treatment
por: Lazarczyk, Maciej Jakub, et al.
Publicado: (2012)

White Matter Changes in Bipolar Disorder, Alzheimer Disease, and Mild Cognitive Impairment: New Insights from DTI
por: Xekardaki, Aikaterini, et al.
Publicado: (2011)

No neuropathological evidence for a direct topographical relation between microbleeds and cerebral amyloid angiopathy
por: Kövari, Enikö, et al.
Publicado: (2015)

Association of Alzheimer’s disease polygenic risk scores with amyloid accumulation in cognitively intact older adults
por: Luckett, Emma S., et al.
Publicado: (2022)

CSF Proteomic Alzheimer’s Disease-Predictive Subtypes in Cognitively Intact Amyloid Negative Individuals
por: Tijms, Betty Marije, et al.
Publicado: (2021)

Sex differences in the neuropathological hallmarks of Alzheimer’s disease: focus on cognitively intact elderly individuals
por: Hu, Yu‐Ting, et al.
Publicado: (2021)

Advances in preclinical evaluation of experimental antibody-drug conjugates
por: Lyons, Scott K., et al.
Publicado: (2021)

Selective familiarity deficits in otherwise cognitively intact aging individuals with genetic risk for Alzheimer's disease
por: Schoemaker, Dorothee, et al.
Publicado: (2015)

SARS-CoV-2 Emergency and Long-Term Cognitive Impairment in Older People
por: Rizzo, Maria Rosaria, et al.
Publicado: (2021)

Amyloid imaging in cognitively normal individuals, at-risk populations and preclinical Alzheimer's disease()
por: Chételat, Gaël, et al.
Publicado: (2013)

Do brain T2/FLAIR white matter hyperintensities correspond to myelin loss in normal aging? A radiologic-neuropathologic correlation study
por: Haller, Sven, et al.
Publicado: (2013)

Development of a Cognitive Composite for Preclinical Alzheimer’s Disease in Korean Older Adults
por: Kim, Minjae, et al.
Publicado: (2023)

Hubris and Sciences
por: Diamandis, Eleftherios P, et al.
Publicado: (2018)

TREM2‐induced activation of microglia contributes to synaptic integrity in cognitively intact aged individuals with Alzheimer's neuropathology
por: Fracassi, Anna, et al.
Publicado: (2022)

Genetic risk factors of Alzheimer’s Disease disrupt resting-state functional connectivity in cognitively intact young individuals
por: Kucikova, Ludmila, et al.
Publicado: (2023)

Baseline cognition is the best predictor of 4-year cognitive change in cognitively intact older adults
por: Schaeverbeke, Jolien M., et al.
Publicado: (2021)

Oral Microbiome and Alzheimer’s Disease
por: Wan, Jason, et al.
Publicado: (2023)

Associations of AT(N) biomarkers with neuropsychiatric symptoms in preclinical Alzheimer’s disease and cognitively unimpaired individuals
por: Ng, Kok Pin, et al.
Publicado: (2021)

Hippocampal and Amygdala Gray Matter Loss in Elderly Controls with Subtle Cognitive Decline
por: Zanchi, Davide, et al.
Publicado: (2017)

Illustrated Neuropathologic Diagnosis of Alzheimer’s Disease
por: Doher, Nicholas, et al.
Publicado: (2023)

Relationship of stigmatization and social support with depression and anxiety among cognitively intact older adults
por: Al-Dwaikat, Tariq N., et al.
Publicado: (2022)

The Older Driver: Who is Responsible? The State, The Doctor, or The Older Driver?
por: Finestone, Albert J
Publicado: (2006)

Translational research on reserve against neurodegenerative disease: consensus report of the International Conference on Cognitive Reserve in the Dementias and the Alzheimer’s Association Reserve, Resilience and Protective Factors Professional Interest Area working groups
por: Perneczky, Robert, et al.
Publicado: (2019)

Associations of healthy lifestyles with cerebrospinal fluid biomarkers of Alzheimer’s disease pathology in cognitively intact older adults: the CABLE study
por: Hou, Xiao-He, et al.
Publicado: (2021)

Alzheimer resemblance atrophy index, BrainAGE, and normal pressure hydrocephalus score in the prediction of subtle cognitive decline: added value compared to existing MR imaging markers
por: Giannakopoulos, Panteleimon, et al.
Publicado: (2022)

Using Optogenetics to Model Cellular Effects of Alzheimer’s Disease
por: Tiwari, Prabhat, et al.
Publicado: (2023)

Ultrasound and dynamic functional imaging in vascular cognitive impairment and Alzheimer’s disease
por: Malojcic, Branko, et al.
Publicado: (2017)

Midlife interventions are critical in prevention, delay, or improvement of Alzheimer’s disease and vascular cognitive impairment and dementia
por: Gandy, Sam, et al.
Publicado: (2017)

Therapeutic Potential of Direct Clearance of the Amyloid-β in Alzheimer’s Disease
por: Kim, Dong Eun, et al.
Publicado: (2020)

A New Bistable Switch Model of Alzheimer’s Disease Pathogenesis
por: Burlando, Bruno, et al.
Publicado: (2022)

Amyloid Cascade Hypothesis for the Treatment of Alzheimer’s Disease: Progress and Challenges
por: Wu, Tong, et al.
Publicado: (2022)

Comparative cognition for conservationists
por: Greggor, Alison L., et al.
Publicado: (2014)

Cognitive and Emotional Determinants of Automatic Perspective Taking in Healthy Adults
por: Rodriguez, Cristelle, et al.
Publicado: (2022)

Absence of amyloid β oligomers at the postsynapse and regulated synaptic Zn(2+) in cognitively intact aged individuals with Alzheimer’s disease neuropathology
por: Bjorklund, Nicole L, et al.
Publicado: (2012)

Impact of Coffee, Wine, and Chocolate Consumption on Cognitive Outcome and MRI Parameters in Old Age
por: Haller, Sven, et al.
Publicado: (2018)

Cerebrospinal Fluid Biomarkers for Alzheimer’s Disease in the Era of Disease-Modifying Treatments
por: Paraskevas, George P., et al.
Publicado: (2021)

Improving the Utility of Polygenic Risk Scores as a Biomarker for Alzheimer’s Disease
por: Vlachakis, Dimitrios, et al.
Publicado: (2021)

Plasma Phospho-Tau-181 as a Diagnostic Aid in Alzheimer’s Disease
por: Tsantzali, Ioanna, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nh3et51c3l82fmc9s165hu2ul6