Cargando…

Phosphorylation of p90RSK is associated with increased response to neoadjuvant chemotherapy in ER-positive breast cancer

BACKGROUND: The clinical implication of Ras/Raf/ERK pathway activity in breast cancer tissue and its association with response to chemotherapy is controversial. We aimed to explore the value of p90RSK phosphorylation, a downstram molecule of the pathway, in predicting chemotherapy response in breast...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moon, Hyeong-Gon, Yi, Jae Kyo, Kim, Hee Sung, Lee, Hea Young, Lee, Kyung-Min, Yi, Minju, Ahn, Sookyung, Shin, Hee-Chul, Ju, Ji-hyun, Shin, Incheol, Han, Wonshik, Noh, Dong-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523086/ https://www.ncbi.nlm.nih.gov/pubmed/23216670 http://dx.doi.org/10.1186/1471-2407-12-585

Ejemplares similares

An objective nodal staging system for breast cancer patients undergoing neoadjuvant systemic treatment
por: Yoo, Tae-Kyung, et al.
Publicado: (2017)

Patients with Concordant Triple-Negative Phenotype between Primary Breast Cancers and Corresponding Metastases Have Poor Prognosis
por: Shin, Hee-Chul, et al.
Publicado: (2016)

Reliability of Sentinel Lymph Node Biopsy after Neoadjuvant Chemotherapy in Breast Cancer Patients
por: Han, Ahram, et al.
Publicado: (2013)

p90RSK Regulates p53 Pathway by MDM2 Phosphorylation in Thyroid Tumors
por: Maietta, Immacolata, et al.
Publicado: (2022)

Enhanced anti-tumor activity and cytotoxic effect on cancer stem cell population of metformin-butyrate compared with metformin HCl in breast cancer
por: Lee, Kyung-Min, et al.
Publicado: (2016)

Correction: Enhanced anti-tumor activity and cytotoxic effect on cancer stem cell population of metformin-butyrate compared with metformin HCl in breast cancer
por: Lee, Kyung-Min, et al.
Publicado: (2021)

Regulation of p90RSK phosphorylation by SARS‐CoV infection in Vero E6 cells
por: Mizutani, Tetsuya, et al.
Publicado: (2006)

RSK2 is required for TRAF6 phosphorylation-mediated colon inflammation
por: Yao, Ke, et al.
Publicado: (2018)

Role of p90RSK in Kidney and Other Diseases
por: Lin, Ling, et al.
Publicado: (2019)

Radiation therapy induces immunosenescence mediated by p90RSK
por: Imanishi, Masaki, et al.
Publicado: (2022)

Inhibition of p90RSK Ameliorates PDGF-BB-Mediated Phenotypic Change of Vascular Smooth Muscle Cell and Subsequent Hyperplasia of Neointima
por: Hwang, Ae-Rang, et al.
Publicado: (2023)

Ionizing Radiation Induces Endothelial Inflammation and Apoptosis via p90RSK-Mediated ERK5 S496 Phosphorylation
por: Vu, Hang Thi, et al.
Publicado: (2018)

RSK2 and ERα comrades-in-arms in homeostasis and transformation
por: Ludwik, Katarzyna A., et al.
Publicado: (2020)

The treatment outcomes and the use of adjuvant therapies in breast cancer patients with severe co-morbidities
por: Han, Jaihong, et al.
Publicado: (2017)

p90Rsk is not involved in cytostatic factor arrest in mouse oocytes
por: Dumont, Julien, et al.
Publicado: (2005)

p90 ribosomal S6 kinase (RSK) phosphorylates myosin phosphatase and thereby controls edge dynamics during cell migration
por: Samson, Shiela C., et al.
Publicado: (2019)

The ribosomal S6 kinase 2 (RSK2)–SPRED2 complex regulates the phosphorylation of RSK substrates and MAPK signaling
por: Lopez, Jocelyne, et al.
Publicado: (2023)

Luteolin suppresses UVB-induced photoageing by targeting JNK1 and p90(RSK2)
por: Lim, Sung H, et al.
Publicado: (2013)

Estradiol promotes the progression of ER+ breast cancer through methylation-mediated RSK4 inactivation
por: Li, Qiuyun, et al.
Publicado: (2019)

Nomogram for Predicting Breast Conservation after Neoadjuvant Chemotherapy
por: Kim, Min Kyoon, et al.
Publicado: (2015)

Transition into inflammatory cancer-associated adipocytes in breast cancer microenvironment requires microRNA regulatory mechanism
por: Lee, Jiwoo, et al.
Publicado: (2017)

The p90rsk-mediated signaling of ethanol-induced cell proliferation in HepG2 cell line
por: Kim, Han Sang, et al.
Publicado: (2016)

Effect of standard low-dose anthracycline chemotherapy on late congestive heart failure in breast cancer survivors aged between 50 and 59 at diagnosis: A nationwide study
por: Chung, Il Yong, et al.
Publicado: (2020)

The interaction of the ER with ERBB2 and PI3K results in elevated levels of AKT and p90(RSK )in tamoxifen-resistant MCF-7 cells
por: Pancholi, S, et al.
Publicado: (2005)

The p90 Ribosomal S6 Kinase (RSK) Is a Mediator of Smooth Muscle Contractility
por: Artamonov, Mykhaylo, et al.
Publicado: (2013)

Reduced proliferation in breast cancer cells contacting the neighboring adipocytes in human breast cancer tissues
por: Ryu, Han Suk, et al.
Publicado: (2015)

Perspective Insight into Future Potential Fusion Gene Transcript Biomarker Candidates in Breast Cancer
por: Kim, Ryong Nam, et al.
Publicado: (2018)

The Clinical Significance and Molecular Features of the Spatial Tumor Shapes in Breast Cancers
por: Moon, Hyeong-Gon, et al.
Publicado: (2015)

FMK, an Inhibitor of p90RSK, Inhibits High Glucose-Induced TXNIP Expression via Regulation of ChREBP in Pancreatic β Cells
por: Han, Jung-Hwa, et al.
Publicado: (2019)

mTORC2 Is Involved in the Induction of RSK Phosphorylation by Serum or Nutrient Starvation
por: Chou, Po-Chien, et al.
Publicado: (2020)

RIOK2 phosphorylation by RSK promotes synthesis of the human small ribosomal subunit
por: Cerezo, Emilie L., et al.
Publicado: (2021)

Phosphorylation of REPS1 at Ser709 by RSK attenuates the recycling of transferrin receptor
por: Kim, Seong Heon, et al.
Publicado: (2021)

A stepwise and digital pattern of RSK phosphorylation determines the outcome of thymic selection
por: Funasaki, Shintaro, et al.
Publicado: (2023)

Comparison of metabolic changes after neoadjuvant endocrine and chemotherapy in ER-positive, HER2-negative breast cancer
por: Ryu, Ho Hyun, et al.
Publicado: (2021)

Hypoxia-Induced Invadopodia Formation Involves Activation of NHE-1 by the p90 Ribosomal S6 Kinase (p90RSK)
por: Lucien, Fabrice, et al.
Publicado: (2011)

Detection of Germline Mutations in Breast Cancer Patients with Clinical Features of Hereditary Cancer Syndrome Using a Multi-Gene Panel Test
por: Shin, Hee-Chul, et al.
Publicado: (2020)

Low Rates of Additional Cancer Detection by Magnetic Resonance Imaging in Newly Diagnosed Breast Cancer Patients Who Undergo Preoperative Mammography and Ultrasonography
por: Kim, Jisun, et al.
Publicado: (2014)

Patient-Reported Outcomes From Phase III Neoadjuvant Systemic Trial Comparing Neoadjuvant Chemotherapy With Neoadjuvant Endocrine Therapy in Pre-Menopausal Patients With Estrogen Receptor-Positive and HER2-Negative, Lymph Node-Positive Breast Cancer
por: Gwark, Sungchan, et al.
Publicado: (2021)

Validation of a Scoring System for Predicting Malignancy in Patients Diagnosed with Atypical Ductal Hyperplasia Using an Ultrasound-Guided Core Needle Biopsy
por: Kim, Jisun, et al.
Publicado: (2012)

Endocrine Treatment-Related Symptoms and Patient Outcomes in Breast Cancer: A Meta-Analysis
por: Yoo, Tae-Kyung, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ab9vr01q40e231f7b3pnbfne8s