Efficacy and safety of eltrombopag in Japanese patients with chronic liver disease and thrombocytopenia: a randomized, open-label, phase II study

BACKGROUND: Eltrombopag is an oral thrombopoietin receptor agonist that stimulates thrombopoiesis and shows higher exposure in East Asian patients than in non-Asian patients. We evaluated the pharmacokinetics, efficacy, and safety of eltrombopag in Japanese patients with thrombocytopenia associated...

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Detalles Bibliográficos
Autores principales: Kawaguchi, Takumi, Komori, Atsumasa, Seike, Masataka, Fujiyama, Shigetoshi, Watanabe, Hiroshi, Tanaka, Masatoshi, Sakisaka, Shotaro, Nakamuta, Makoto, Sasaki, Yutaka, Oketani, Makoto, Hattori, Toshihiro, Katsura, Koichi, Sata, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2012
Materias:
Original Article—Liver, Pancreas, and Biliary Tract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523116/
https://www.ncbi.nlm.nih.gov/pubmed/22674141
http://dx.doi.org/10.1007/s00535-012-0600-5

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