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Wild type and K897T polymorphisms of the hERG gene: modeling the APD in Caucasians
The presented study aims to assess the possibility of simulating changes in cardiac cell electrophysiology due to K897T polymorphism in the Caucasian population. In the first part of the experiment, the parameters of the equations describing channel gating were fitted to the experimental data. Then,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Biomedical Informatics
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523219/ https://www.ncbi.nlm.nih.gov/pubmed/23251039 http://dx.doi.org/10.6026/97320630081062 |