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Homology modeling and structural analysis of human P-glycoprotein

Homology modeling and structural analysis of human P-glycoprotein (hP-gp) were performed with a software package the Molecular Operating Environment (MOE). A mouse P-gp (mP-gp; PDB code: 3G5U) was selected as a template for the 3D structure modeling of hP-gp. The modeled hP-gp showed significant 3D...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Hideaki, Kidachi, Yumi, Kamiie, Katsuyoshi, Noshita, Toshiro, Umetsu, Hironori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523220/
https://www.ncbi.nlm.nih.gov/pubmed/23251040
http://dx.doi.org/10.6026/97320630081066