Refractory Gout Attack

Refractory gout attack is an uncommon problem, since gout flares are usually self-limited. This clinical condition is characterized by serum uric acid higher than 6 mg/Dl or continuous manifestations of recurrent flares, chronic arthritis, and increased tophi. We report in this paper a 69-year-old m...

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Detalles Bibliográficos
Autores principales: Fargetti, Simone, Goldenstein-Schainberg, Claudia, Silva Abreu, Andressa, Fuller, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523317/
https://www.ncbi.nlm.nih.gov/pubmed/23304159
http://dx.doi.org/10.1155/2012/657694
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author Fargetti, Simone
Goldenstein-Schainberg, Claudia
Silva Abreu, Andressa
Fuller, Ricardo
author_facet Fargetti, Simone
Goldenstein-Schainberg, Claudia
Silva Abreu, Andressa
Fuller, Ricardo
author_sort Fargetti, Simone
collection PubMed
description Refractory gout attack is an uncommon problem, since gout flares are usually self-limited. This clinical condition is characterized by serum uric acid higher than 6 mg/Dl or continuous manifestations of recurrent flares, chronic arthritis, and increased tophi. We report in this paper a 69-year-old man with a polyarticular and protracted gout attack, despite usual treatment and low urate sera levels. In order to manage this problem, we reviewed gout pathophysiology and developed a therapeutic solution based on benzbromarone pharmacokinetics. We also review herein new options for gout treatment that could be used in similar cases.
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spelling pubmed-35233172013-01-09 Refractory Gout Attack Fargetti, Simone Goldenstein-Schainberg, Claudia Silva Abreu, Andressa Fuller, Ricardo Case Rep Med Case Report Refractory gout attack is an uncommon problem, since gout flares are usually self-limited. This clinical condition is characterized by serum uric acid higher than 6 mg/Dl or continuous manifestations of recurrent flares, chronic arthritis, and increased tophi. We report in this paper a 69-year-old man with a polyarticular and protracted gout attack, despite usual treatment and low urate sera levels. In order to manage this problem, we reviewed gout pathophysiology and developed a therapeutic solution based on benzbromarone pharmacokinetics. We also review herein new options for gout treatment that could be used in similar cases. Hindawi Publishing Corporation 2012 2012-11-25 /pmc/articles/PMC3523317/ /pubmed/23304159 http://dx.doi.org/10.1155/2012/657694 Text en Copyright © 2012 Simone Fargetti et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Fargetti, Simone
Goldenstein-Schainberg, Claudia
Silva Abreu, Andressa
Fuller, Ricardo
Refractory Gout Attack
title Refractory Gout Attack
title_full Refractory Gout Attack
title_fullStr Refractory Gout Attack
title_full_unstemmed Refractory Gout Attack
title_short Refractory Gout Attack
title_sort refractory gout attack
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523317/
https://www.ncbi.nlm.nih.gov/pubmed/23304159
http://dx.doi.org/10.1155/2012/657694
work_keys_str_mv AT fargettisimone refractorygoutattack
AT goldensteinschainbergclaudia refractorygoutattack
AT silvaabreuandressa refractorygoutattack
AT fullerricardo refractorygoutattack

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