Cargando…

The treatment strategies of autoimmune disease may need a different approach from conventional protocol: A review

Autoimmune disease (AD) is one of the emerging noncommunicable diseases. Remission is a possibility in AD, but current treatment strategies are not able to achieve this. We have well-established protocols for infections, oncology, metabolic diseases, and transplantation which are often used as model...

Descripción completa

Detalles Bibliográficos
Autor principal: Chandrashekara, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523489/
https://www.ncbi.nlm.nih.gov/pubmed/23248391
http://dx.doi.org/10.4103/0253-7613.103235
_version_ 1782253213243670528
author Chandrashekara, S.
author_facet Chandrashekara, S.
author_sort Chandrashekara, S.
collection PubMed
description Autoimmune disease (AD) is one of the emerging noncommunicable diseases. Remission is a possibility in AD, but current treatment strategies are not able to achieve this. We have well-established protocols for infections, oncology, metabolic diseases, and transplantation which are often used as models for the management of AD. Studies and observations suggest that in contrast to diseases used as a role model, AD has wide variability, different causative and pathogenic process, which is highly dynamic, making the current treatment strategies to fall short of expected complete remission. In this brief review, it is attempted to highlight the current understanding of AD and the probable gaps in the treatment strategies. Few hypothetical suggestions to modify the treatment protocols are presented.
format Online
Article
Text
id pubmed-3523489
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-35234892012-12-17 The treatment strategies of autoimmune disease may need a different approach from conventional protocol: A review Chandrashekara, S. Indian J Pharmacol Educational Forum Autoimmune disease (AD) is one of the emerging noncommunicable diseases. Remission is a possibility in AD, but current treatment strategies are not able to achieve this. We have well-established protocols for infections, oncology, metabolic diseases, and transplantation which are often used as models for the management of AD. Studies and observations suggest that in contrast to diseases used as a role model, AD has wide variability, different causative and pathogenic process, which is highly dynamic, making the current treatment strategies to fall short of expected complete remission. In this brief review, it is attempted to highlight the current understanding of AD and the probable gaps in the treatment strategies. Few hypothetical suggestions to modify the treatment protocols are presented. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3523489/ /pubmed/23248391 http://dx.doi.org/10.4103/0253-7613.103235 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Educational Forum
Chandrashekara, S.
The treatment strategies of autoimmune disease may need a different approach from conventional protocol: A review
title The treatment strategies of autoimmune disease may need a different approach from conventional protocol: A review
title_full The treatment strategies of autoimmune disease may need a different approach from conventional protocol: A review
title_fullStr The treatment strategies of autoimmune disease may need a different approach from conventional protocol: A review
title_full_unstemmed The treatment strategies of autoimmune disease may need a different approach from conventional protocol: A review
title_short The treatment strategies of autoimmune disease may need a different approach from conventional protocol: A review
title_sort treatment strategies of autoimmune disease may need a different approach from conventional protocol: a review
topic Educational Forum
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523489/
https://www.ncbi.nlm.nih.gov/pubmed/23248391
http://dx.doi.org/10.4103/0253-7613.103235
work_keys_str_mv AT chandrashekaras thetreatmentstrategiesofautoimmunediseasemayneedadifferentapproachfromconventionalprotocolareview
AT chandrashekaras treatmentstrategiesofautoimmunediseasemayneedadifferentapproachfromconventionalprotocolareview