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Immunotherapy of Malignant Disease Using Chimeric Antigen Receptor Engrafted T Cells

Chimeric antigen receptor- (CAR-) based immunotherapy has been under development for almost 25 years, over which period it has progressed from a new but cumbersome technology to an emerging therapeutic modality for malignant disease. The approach involves the genetic engineering of fusion receptors...

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Detalles Bibliográficos
Autor principal: Maher, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523553/
https://www.ncbi.nlm.nih.gov/pubmed/23304553
http://dx.doi.org/10.5402/2012/278093