Placental Hofbauer cells limit HIV-1 replication and potentially offset mother to child transmission (MTCT) by induction of immunoregulatory cytokines

BACKGROUND: Despite readily detectable levels of the HIV-1 (co)-receptors CD4, CCR5 and DC-SIGN on placental macrophages (Hofbauer Cells [HCs]), the rate of HIV-1 infection in utero in the absence of interventions is only 7% of exposed infants. Here, we examine the replication kinetics of human HCs...

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Detalles Bibliográficos
Autores principales: Johnson, Erica L, Chakraborty, Rana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524025/
https://www.ncbi.nlm.nih.gov/pubmed/23217137
http://dx.doi.org/10.1186/1742-4690-9-101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524025/
https://www.ncbi.nlm.nih.gov/pubmed/23217137
http://dx.doi.org/10.1186/1742-4690-9-101

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